Monteloeder has introduced a natural botanical composition called BeRelief, which has been formulated to alleviate musculoskeletal discomfort and enhance overall well-being.
The Spanish firm, which is a subsidiary of nutraceuticals provider SuanNutra, claims to have used machine learning tools to develop this formulation.
BeRelief is a proprietary blend featuring botanical extracts like ashwagandha, rosemary, and sesame.
The biotechnology company has used these active compounds to work together in inhibiting receptors associated with discomfort.
The ingredient was developed with support from the Center for Technological Development and Innovation (CDTI Innovation). Its development was co-financed by the European Union’s FEDER funds.
BeRelief is the result of research that started with the preselection of nutrients from a library of 50,000 natural compounds.
Using advanced deep technology platforms, the selection process screened phytochemicals for their molecular interactions with various discomfort receptors, including TRPV1, Nav1.7, TrkA, and nAChR.
According to Monteloeder, these receptors are involved in transmitting discomfort signals, sensitising neurons to soreness, and influencing pain perception.
Monteloeder chief research and development officer Nuria Caturla said: “In recent years, machine learning has emerged as a key technology in discovering and developing innovative compounds.
“We took it one step further, helping create a nutraceutical that can help us cope with today’s hectic life and improve well-being.”
The selection criteria for BeRelief included precise physicochemical attributes. Once the optimal compounds were identified, the botanical sources were obtained and subjected to comprehensive characterisation.
The process included a complete analysis of their active content and traditional properties.
BeRelief was developed to leverage the complementary and synergistic effects of these actives.
The ingredients in BeRelief were chosen for their potential individual and synergistic effects in slowing channels involved in sensory transmission and perception.
Monteloeder recently conducted a double-blind clinical study that confirmed that BeRelief reduces back pain.
The 12-week trial involved 135 participants with back and neck pain.
Those taking BeRelief experienced a significant and lasting reduction in discomfort compared to the placebo group, said the company
Additionally, users of this botanical blend reported improvements in mood and sleep quality.
