Ingredients maker BioCell Technology said that a recent clinical study has confirmed that its BioCell Collagen (Cosmetic Grade) CG ingredient is non-comedogenic and gentle on pores.
BioCell Collagen CG is an ingredient used in topical cosmetic products.
Researchers evaluated it in a trial conducted over four weeks on a test panel of both women and men to assess the ingredient for comedogenicity, adverse effects, and any unexpected reactions.
BioCell Technology said that previous studies have demonstrated that BioCell Collagen CG is hypoallergenic and does not exhibit cytotoxicity on human skin cells.
The company is focused on research and development in science-based ingredients for dietary supplements, functional foods, and cosmetics.
BioCell Technology CEO Mo Ishaq said: “We’ve made a significant investment in the development of BioCell Collagen CG and this independent third-party research validates the non-comedogenic and pore-friendly performance we have observed with this ingredient for years.
“Scientific validation is core to our mission and what we provide to our customers as proof points for our industry-leading ingredients.”
Advanced Science Laboratories assembled a diverse panel of women and men, pre-screened them, and adhered to clinical protocols for comedogenicity testing.
The study maintained specific conditions, including allowing participants to continue their usual hygiene and cosmetic routines.
All participants were over 18 and free from dermatological or systemic disorders that might affect the testing and outcomes.
Researchers assessed the comedogenicity of BioCell Collagen CG by applying a saturated pad of the test material to the suprascapular region of each panellist’s back.
The patch application was repeated every other day, totalling three applications per week over four weeks. Each patch was removed after 48 hours, and the sites were then cleaned and inspected for signs of irritation.
Following the final patch removal, follicular biopsies were performed using a cyanoacrylate adhesive on glass slides applied to the test area.
The biopsy slides were analysed under a microscope to count the follicles and microcomedones.
The mean number of follicles and comedones per square centimetre was calculated, resulting in a comedogenic score of 0.07, indicating minimal microcomedones.
Furthermore, no adverse effects or unexpected reactions were observed in any of the participants throughout the study.
